Apple makes things so easy!
To turn off the annoying printer message that pops up EVERY TIME YOU PRINT ON LARGE PAPER, simply research the CUPS print server documentation for a half hour, find the IP address of your printer, open the Unix Terminal app to type in the command line which will enable the web interface, navigate to your printers, click on the printer whose defaults you want to save (if it is available, otherwise restart your computer and start over), work your way through all the pages until you find the defaults for "Request Offset," set it to "no," click SAVE, type in your admin username ("admin" will not work and neither will your ShortName, but you'll find that out the hard way), type in your system password, authorize the changes, exit out of the CUPS web interface, restart your computer... AND THERE YOU GO! NO MORE ANNOYING POP-UPS EVERY TIME YOU FUCKING PRINT! IT'S JUST THAT EASY!!! AREN'T YOU GLAD YOU BOUGHT A FUCKING MAC?!???
Look, I realize that Apple is not wanting people to print stuff to save the planet and all that... but there are people who actually have to print stuff. The fact that they don't want to make such a basic function of their operating system be easy to use and manage is reeeeally telling on the "It just works" company.